产品介绍
Product Description
Application
(R)(−)-α-Methylhistamine dihydrochloride has been used as an agonist for the histamine H3 cell lines. It has also been used in the antagonist assay for the histamine H3 cell lines.
Biochem/physiol Actions
(R)(−)-α-Methylhistamine dihydrochloride is a potent, selective H3 histamine receptor agonist which crosses the blood-brain barrier. It can inhibit histamine synthesis and release.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| optical activity | [α]22/D −4°, c = 0.8 in H2O(lit.) |
| storage condition | desiccated |
| color | white to off-white |
| solubility | H2O: soluble |
| web metadata keyword.default | (R)-alpha-methylhistamine; (R-alpha-MeHa); H3; receptor; histamine activator; histamine agonist; epithelial cell growth; PNS; CNS; azomethine; |
| SMILES string | Cl.Cl.C[C@@H](N)Cc1c[nH]cn1 |
| InChI | 1S/C6H11N3.2ClH/c1-5(7)2-6-3-8-4-9-6;;/h3-5H,2,7H2,1H3,(H,8,9);2*1H/t5-;;/m1../s1 |
| InChI key | IZHCNQFUWDFPCW-ZJIMSODOSA-N |
| Gene Information | human ... HRH3(11255) |
