产品介绍
Product Description
Biochem/physiol Actions
Inhibitor of cyclooxygenase 2 (COX-2) and the carbonic anhydrases CAI and CAII
Polmacoxib is a nonsteroidal anti-inflammatory drug (NSAID) that acts as an inhibitor of cyclooxygenase 2 (COX-2) and the carbonic anhydrases CAI and CAII. It has also been found to inhibit colorectal adenoma and tumor growth in mouse models.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | NS(C1=CC=C(C=C1)C(OC2(C)C)=C(C2=O)C3=CC=CC(F)=C3)(=O)=O |
| InChI | 1S/C18H16FNO4S/c1-18(2)17(21)15(12-4-3-5-13(19)10-12)16(24-18)11-6-8-14(9-7-11)25(20,22)23/h3-10H,1-2H3,(H2,20,22,23) |
| InChI key | IJWPAFMIFNSIGD-UHFFFAOYSA-N |
