General description
14 kDa calculated
Lymphocyte antigen 6C2 (Ly6C) is a 131 AA long membrane protein that is linked to macrophage phenotype according to expression levels.
Immunogen
Whole cells expressing mouse Ly6C.
Application
Detect Lymphocyte antigen 6C2 using this rat monoclonal antibody, Anti-Ly6C Antibody, clone 6C3 validated for use in Flow Cytometry & Dot Blot.
Dot Blot Analysis: A representative lot from an independent laboratory detected Ly6C in bone marrow-derived monocytes expressing 6C3 (Butovsky, O., et al. (2012). J Clin Invest. 122(9):3063-3087.).
Research Category
Neuroscience
Research Sub Category
Signaling Neuroscience
Physical form
Format: Purified
Protein G Purified
Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Evaluated by Flow Cytometry in mouse spleen cells.
Flow Cytometry Analysis: 1 µg of this antibody detected Ly6C in 1X10E6 mouse spleen cells.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rat |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 6C3, monoclonal |
| species reactivity | mouse |
| technique(s) | dot blot: suitable,flow cytometry: suitable |
| isotype | IgG2aκ |
| NCBI accession no. | NP_001092687 |
| UniProt accession no. | P0CW03 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | mouse ... Ly6C1(17067) |
