General description
Chromodomain-helicase-DNA-binding protein 3, more commonly known as CHD-3, is a member of the CHD family of proteins. These proteins are characterized by the presence of chromo (chromatin organization modifier) domain, SNF2-related helicase/ATPase domain, and and a carboxy-terminal DNA binding domain. As a component of the Mi-2/NuRD histone deacetylase complex, CHD-3 participates in chromatin remodeling by deacetylating histones.
~ 250 kDa observed
Immunogen
Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of human CHD-3.
Application
Anti-CHD-3 Antibody is a Rabbit Polyclonal Antibody for detection of CHD-3 also known as Chromodomain-helicase-DNA-binding protein 3, hZFH & has been validated in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Chromatin Biology
Biochem/physiol Actions
This antibody recognizes CHD-3 at the C-terminus.
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
HeLa cell lysate
Evaluated by Western Blot in HeLa cell lysate.
Western Blot Analysis: 0.05 µg/mL of this antibody detected CHD-3 on 10 µg of HeLa cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: MABE482
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | human |
| technique(s) | western blot: suitable |
| NCBI accession no. | NP_001005273 |
| UniProt accession no. | Q12873 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... CHD3(1107) |
