产品介绍
Product Description
Biochem/physiol Actions
Cilastatin sodium is an inhibitor of the renal enzyme dehydropeptidase I and some bacterial zinc-containing β-lactamases.
Cilastatin sodium is an inhibitor of the renal enzyme dehydropeptidase I and some bacterial zinc-containing β-lactamases. By this action, cilastatin suppresses both host and target metabolism of the broad-spectrum antibiotic imipenem, improving its efficacy.
技术参数
Specifications
| form | liquid (1:1 DMSO:H2O) |
| Quality Segment | 200 |
| concentration | 50 mg/mL in DMSO/H2O, 1:1 |
| shipped in | dry ice |
| storage temp. | −20°C |
| SMILES string | [Na+].S(C[C@@H](N)C(=O)[O-])CCCC\C=C(/NC(=O)[C@@H]1C(C1)(C)C)\C(=O)O |
| InChI | 1S/C16H26N2O5S.Na/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21;/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/b12-6-;/t10-,11-;/m1./s1 |
| InChI key | QXPBTTUOVWMPJN-VQAYNFQASA-M |
