General description
Albumin constitutes 25% of the proteins produced by the liver and is a prominent protein found in the blood. It is a protein of a single polypeptide chain with a thiol group.
Application
该重组变异建议用于:吸收、分散、代谢和排泄(ADME)药理学研究;细胞培养;药物递送研究;细胞冻存。
Albumin human has been used:
- to study its adsorption process on model mica surface at pH 3.5 using the atomic force microscopy (AFM) and in situ streaming potential measurements
- to study its proteolytic activities under reducing conditions
- in the medium for stem cell cultivation
Biochem/physiol Actions
Albumin is a binding and transport protein that serves as a protein repository and a carrier for amino acids. Albumin binding dissolves the biomolecules in blood and ensures its effective transport. This also prevents the loss of substance through excretion. Pathological conditions like vasculitis, lymphangiectasia, glomerulonephritis, and hepatic sinusoidal hypertension might result in hypoalbuminemia. This product can be used in the pharmaceutical industry as a drug excipient and to coat medical devices.
白蛋白是可见于动物体液和组织及部分植物种子的一类可溶性单体蛋白。 血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白。 血清白蛋白在调节血液的胶体渗透压方面也至关重要。
Analysis Note
经过内毒素检测
Other Notes
更多信息参见人血清白蛋白。
| biological source | human |
| Quality Level | 200 |
| recombinant | expressed in Saccharomyces cerevisiae |
| assay | ≥99% (agarose gel electrophoresis) |
| form | aqueous solution |
| mol wt | monomer ~67 kDa |
| concentration | 10% in aqueous buffer |
| technique(s) | cell culture | mammalian: suitable |
| UniProt accession no. | P02768 |
| storage temp. | 2-8°C |
| SMILES string | FC(F)(F)C(F)(F)C(F)(F)F |
| InChI | 1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11 |
| InChI key | QYSGYZVSCZSLHT-UHFFFAOYSA-N |
| Gene Information | human ... ALB(213) |

