产品介绍
Product Description
Biochem/physiol Actions
Gabexate mesylate is a competitive inhibitor of serine proteases that displays high selectivity for TMPRSS2 (Transmembrane protease serine 2) (IC50 = 130 nM) with little or no activity towards several MMPs, caspases and USPs (>> 10 μM). Gabexate mesylate was reported to decrease inflammatory cytokines production and be useful as an anticoagulant.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥97% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | H2O: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | CS(O)(=O)=O.CCOC(=O)c1ccc(OC(=O)CCCCCNC(N)=N)cc1 |
| InChI | 1S/C16H23N3O4.CH4O3S/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18;1-5(2,3)4/h7-10H,2-6,11H2,1H3,(H4,17,18,19);1H3,(H,2,3,4) |
| InChI key | DNTNDFLIKUKKOC-UHFFFAOYSA-N |
