产品介绍
Product Description
Biochem/physiol Actions
NBD-556 is small molecule mimetic of CD4 that recognizes the HIV-1 envelope protein gp120.
NBD-556 is small molecule mimetic of CD4. NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding. The CD4-induced conformational change in gp120 is necessary for interaction with CCR5.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 15 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | Clc1ccc(cc1)NC(=O)C(=O)NC2CC(NC(C2)(C)C)(C)C |
| InChI | 1S/C17H24ClN3O2/c1-16(2)9-13(10-17(3,4)21-16)20-15(23)14(22)19-12-7-5-11(18)6-8-12/h5-8,13,21H,9-10H2,1-4H3,(H,19,22)(H,20,23) |
| InChI key | ZKXLQCIOURANAD-UHFFFAOYSA-N |
