产品介绍
Product Description
Biochem/physiol Actions
Prodrug form of paliperidone, is a long-acting injectable antipsychotic that targets dopamine and serotonin receptors.
Paliperidone palmitate is a long-acting injectable form of paliperidone, an atypical antipsychotic that targets dopamine D2 and serotonin 5-HT2A receptors to alleviate schizophrenia symptoms through neurotransmission regulation. Paliperidone palmitate also interacts with α1/α2 adrenergic and H1 histaminergic receptors, influencing both its therapeutic effects and side effect profile. The formulation′s sustained release mechanism promotes gradual absorption, ensuring stable drug levels for prolonged efficacy.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | soluble (DMSO:TFA, 2 mg/mL, clear (add 1 drop TFA)) |
| storage temp. | -10 to -25°C |
| SMILES string | Fc1cc2[o]nc(c2cc1)C3CCN(CC3)CCC4=C(NC5=C(CCCN5C4=O)OC(=O)CCCCCCCCCCCCCCC)C |
| InChI key | YOSKWMGLLZWACB-UHFFFAOYSA-N |

