产品介绍
Product Description
General description
Quisqualate/ Quisqualic acid is obtained from the fruits and seeds of Quisqualis chinensis. It is an agonist at two subsets of excitatory amino acid receptors metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores and, ionotropic receptors that directly control membrane channels. L-quisqualic acid is an agonist of the neurotransmitter L-glutamate.
Application
Quisqualic acid has also been used as a group I metabotropic receptor agonist in neurons.
Quisqualic acid has been used to test ligand-gated receptors in spiral ganglion neurons.
Biochem/physiol Actions
Active enantiomer of quisqualic acid; excitatory amino acid at glutamate receptors.
技术参数
Specifications
| form | powder |
| Quality Segment | 200 |
| color | white to off-white |
| solubility | ethanol: <0.17 mg/mL,H2O: 0.5 mg/mL,0.1 M HCl: 1.4 mg/mL,1 M NH4OH: 20 mg/mL,organic solvents: insoluble |
| storage temp. | 2-8°C |
| SMILES string | N[C@@H](CN1OC(=O)NC1=O)C(O)=O |
| InChI | 1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1 |
| InChI key | ASNFTDCKZKHJSW-REOHCLBHSA-N |
| Gene Information | rat ... Gria1(50592), Grik1(29559), Grin2a(24409), Grm1(24414), Grm2(24415), Grm4(24417), Grm5(24418) |
