产品介绍
Product Description
Biochem/physiol Actions
GZ-11608 is a potent and selective inhibitor of vesicular monoamine transporter-2 (VMAT2) that diminished hERG interaction. GZ-11608 reduces behavioral effects of methamphetamine such as locomotor activity, self-administration, and methamphetamine seeking behavior. It does not exhibit abuse liability. GZ-11608 inhibits methamphetamine-induced dopamine release from isolated synaptic vesicles from brain dopaminergic neurons.
Potent and selective inhibitor of vesicular monoamine transporter-2 (VMAT2)
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | oil |
| color | colorless to brown |
| storage temp. | 2-8°C |
| SMILES string | N([C@H](Cc2ccccc2)C)CCCc1ccc(cc1)OC |
| InChI key | LKTLDVZCNLGHOG-INIZCTEOSA-N |
