产品介绍
Product Description
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规格 |
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| Accession Number: | NP_002731 |
| Kinase Group: | Ser⁄Thr Kinases: AGC Group |
| Shipping Condition: | Dry Ice |
| Expression System: | Baculovirus |
| Form: | Frozen |
| Protein Form: | Full Length |
| Research Category: | Drug Development |
| Species: | Human |
| Validated Application: | Kinase Assay |
| Molecular Weight: | 71.5 kDa |
| Gene Alias: | PRKCI (PKC iota) |
| KinaseFamily: | PKC Kinase Family |
| Protein Tag: | His Tag |
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储存 |
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Storage Buffer: 20mM HEPES, pH 7.5, 150mM NaCl, 0.5mM EGTA, 0.5mM EDTA, 0.05% NP-40, 5mM DTT, 50% glycerol Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws. |
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描述 |
The PKC family of serine⁄threonine kinases, including PRKCI (PKC iota), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent.
