General description
46 kDa
Bone morphogenetic protein-7 (BMP-7), also known as osteogenic protein-1, is a member of the TGF- superfamily, and is widely expressed during embryonic development. Like other members of the bone morphogenetic protein family, BMP-7 works synergistically with BMP-2 to play a key role in the differentiation of mesenchymal cells into bone and cartilage tissues by actively recruiting stem cells from the surrounding tissue, thereby initiating the bone formation cascade. In adult cells, BMP-7 is predominately expressed in the brain, kidneys, and bladder.
Application
Immunohistochemistry: Recommended working dilution is 1:50.
Western Blotting: Recommended working concentration is 1 – 2 µg/mL.
This Anti-BMP-7 Antibody, clone 2A10 is validated for use in WB, IH for the detection of BMP-7.
Biochem/physiol Actions
Reactivity with other species has not been tested.
Physical form
Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4),
150 mM NaCl, and 0.05% sodium azide.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified antibody |
| antibody product type | primary antibodies |
| clone | 2A10, monoclonal |
| species reactivity | mouse, human |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| input | sample type mesenchymal stem cell(s) |
| isotype | IgG1κ |
| UniProt accession no. | P18075 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... BMP7(655) mouse ... Bmp7(12162) |
