General description
冈田酸的水溶性类似物（目录号495604）。抑制蛋白磷酸酶1和2A。
Biochem/physiol Actions
主要靶标
PP1，PP2A
产物不与ATP竞争。
可逆：否
细胞渗透性：否
Other Notes
Gjertsen, B.T., et al. 1994.J. Cell Sci.107, 3363.
Kiguchi, K., et al. 1994.Cell Growth Differentiation5, 995.
Ohaka, Y., et al. 1993.Biochem.Biophys.Res. Commun.197, 916.
Gopalakrishna, R., et al. 1992.Biochem.Biophys.Res. Commun.189, 950.
Kreienbuhl, P., et al. 1992.Blood80, 2911.
Normura, M., et al. 1992.Biochemistry31, 11915.
Song, Q., et al. 1992.J. Cell Physiol.153, 550.
Tada, T., et al. 1992.Immunopharmacol.24, 17.
Cohen, P., et al. 1990.Trends Biochem.Sci.15, 98.
Cohen, P., et al. 1989.Annu.Rev. Biochem.58, 453.
Cohen, P., and Cohen, P.T.W.1989.J. Biol. Chem.264, 21435.
Haystead, T.A.J., et al. 1989.Nature337, 78.
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Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：有毒（F）
| Quality Level | 100 |
| assay | ≥98% (TLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,protect from light |
| color | white |
| solubility | water: 1 mg/mL,DMSO: 20 mg/mL,ethanol: 20 mg/mL |
| shipped in | ambient |
| storage temp. | −20°C |
| SMILES string | [N+H4].[O-]C(=O)[C@](O)(C[C@H]1O[C@]2(O[C@@H](CC(=C2)C)[C@H](C)\C=C\[C@@H]3O[C@@]4(O[C@H]5[C@@H](C(=C)[C@H](OC5CC4)[C@@H](O)C[C@@H](C6O[C@]7(OCCCC7)CC[C@H]6C)C)O)CC3)[C@@H](CC1)O)C |
| InChI | 1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1 |
| InChI key | ZBOMSHVRJSJGNR-JBNKPAQWSA-N |
