产品介绍
Product Description
General description
一种细胞渗透性氨基水杨酸化合物，可结合Stat3-SH2结构域并阻止Stat3磷酸化/激活、二聚化、DNA结合和Stat3依赖性转录。显示在体外培养（有效浓度≤100 µM）和体内鼠异种移植模型（5 mg/kg，i.v.）中抑制Stat3依赖性肿瘤生长。也可以50 mM的DMSO溶液（目录号573130）提供。
Packaging
用惰性气体包装
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：监管审查（Z）
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥95% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,protect from light |
| color | light beige |
| solubility | DMSO: 10 mg/mL (Use only fresh, anhydrous DMSO.) |
| shipped in | ambient |
| storage temp. | −20°C |
| SMILES string | [S](=O)(=O)(OCC(=O)Nc2cc(c(cc2)C(=O)O)O)c1ccc(cc1)C |
| InChI | 1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21) |
| InChI key | HWNUSGNZBAISFM-UHFFFAOYSA-N |
