Immunogen
Epitope: N-terminus fragment
Amino Terminal Fragment of uPA
Application
Detect Urokinase using this Anti-Urokinase Antibody, N-terminus fragment, clone 2G6.2 validated for use in ELISA & WB.
Research Category
Metabolism
Research Sub Category
Enzymes & Biochemistry
Western blot: 1:1000-1:3000
ELISA
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Urokinase Plasminogen Acitivator is a serine protease (SERPIN) that converts plasminogen into the active protease plasmin. UPA is secreted from cells in as the inactive 52 kDa single chain precursor which is activated to the two chain form consisting of an alpha and beta chain.MAB7776 is specific for Human uPA, other species not tested.
Physical form
Format: Purified
Purified immunoglobulin. Liquid in 0.02 M phosphate buffer containing 0.25 M NaCl2 and 0.1% NaN3.
Preparation Note
Maintain refrigerated at 2-8°C in undiluted aliquots for up to 6 months.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 2G6.2, monoclonal |
| species reactivity | human |
| manufacturer/tradename | Chemicon® |
| technique(s) | ELISA: suitable,western blot: suitable |
| isotype | IgG1 |
| NCBI accession no. | NM_002658.2 |
| UniProt accession no. | P00749 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... PLAU(5328) |
