General description
Nudix hydrolase 16 like 1 (NUDT16L1) protein belongs to a nucleoside diphosphate-linked moiety X (Nudix) hydrolases family. It is also known as TIRR (tudor interacting repair regulator), which specifically interacts with the ionizing radiation induced foci formation (IRIF) region of P53 binding protein 1 (53BP1). NUDT16L1 gene is located on human chromosome 16p13.3.
Immunogen
Synthetic peptide directed towards the middle region of human NUDT16L1
Biochem/physiol Actions
Nudix hydrolase 16 like 1 (NUDT16L1) repairs double strand breaks by masking the histone methyl-lysine binding function of P53 binding protein 1 (53BP1). NUDT16L1 acts as an inhibitor of 53BP1.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: LNRVLGLGLGCLRLTEADYLSSHLTEGPHRVVAHLYARQLTLEQLHAVEI
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 23 kDa |
| species reactivity | mouse, dog, rat, human, bovine, guinea pig, rabbit |
| concentration | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no. | NM_032349 |
| UniProt accession no. | Q9BRJ7 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... NUDT16L1(84309) |
