产品介绍
Product Description
General description
人乙酰辅酶A羧化酶2(ACC2)(IC50 = 2.8 µM)的细胞渗透性和选择性抑制剂,在体外浓度高达100 µM下不会抑制人ACC1。 它还显示出抑制酵母菌的生长(IC50 = 3.8 µM),其中天然ACC1基因被人ACC2菌株替代;但浓度为≤ 100 µM的人ACC1菌株则没有。在浓度高达10 µM的培养中,该化合物对人细胞没有毒性。
Preparation Note
在复溶后,分装并冷冻保存(-20°C)。储备溶液在-20°C下可稳定保存至多3个月。
Other Notes
Marjanovic, J., et al. 2010 Proc.Natl.Acad.Sci.107, 9093.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性:标准处理(A)
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥90% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze |
| color | off-white |
| solubility | DMSO: 50 mg/mL |
| shipped in | ambient |
| storage temp. | 2-8°C |

