General description
90-120 kDa
p120 Catenin is a cadherin-associated protein that binds intracellular proteins, such as the small GTPase, RhoA, and controls E-cadherin funcation and stability. Proteins of the p120 family and their isoforms are expressed in cells via alternative splicing, and all of them are essential for HGF signaling to Rac1.
Immunogen
Epitope: C-terminus
Recombinant fusion protein derived from the C-terminus of murine p120
Application
Immunocytochemistry:
Research Category
Signaling
Research Sub Category
Transcription Factors
Use Anti-p120 Catenin Antibody, clone 15D2 (mouse monoclonal antibody) validated in WB, ICC, FC to detect p120 Catenin also known as Cadherin-associated Src substrate ,catenin (cadherin-associated protein) delta 1.
Biochem/physiol Actions
Recognizes p120 Catenin
Physical form
Format: Purified
Protein G Chromatography
Purified mouse monoclonal in 0.1M Tris-Glycine (pH 7.4), 150mM NaCl and 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8ºC from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.
Analysis Note
Control
Hela cell lysate.
Evaluated by Western Blot on Hela cell lysate.
Western Blot Analysis: 1 g/mL of this antibody detected p120 Catenin in lysate from Hela cells.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 04-237
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified antibody |
| antibody product type | primary antibodies |
| clone | 15D2, monoclonal |
| species reactivity | mouse, human |
| species reactivity (predicted by homology) | rat |
| technique(s) | flow cytometry: suitable,immunocytochemistry: suitable,western blot: suitable |
| isotype | IgG1κ |
| UniProt accession no. | O60716 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... CTNND1(1500) |
