General description
N-terminal His6-tagged recombinant human Tie2 residues 771-end
Tie2
Application
Research Category
Metabolism
Inflammation & Immunology
Research Sub Category
Obesity
Metabolic Disorders
Osteoporosis
Arthritis
Biochem/physiol Actions
Protein Target: Tie2
Target Sub-Family: TK
Packaging
2 vials at 5μg each
Also available in 250μg size (2x125μg)--call for pricing and availability and reference catalog number 14-540M when ordering the 250μg size.
Also available in 10 μg size and in bulk
Physical form
Ni2+/NTA-agarose
Preparation Note
6 months at -70C
Analysis Note
routinely evaluated by phosphorylation of Poly (Glu4-Tyr) (4:1)
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | human |
| Quality Segment | 100 |
| recombinant | expressed in baculovirus infected Sf21 cells |
| product line | Upstate® |
| specific activity | (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.) |
| mol wt | Mw 42 kDa |
| purified by | (Ni2+/NTA-agarose) |
| species reactivity | human |
| manufacturer/tradename | Upstate® |
| technique(s) | activity assay: suitable (kinase) |
| accession no. | (FUNCTION: SwissProt: Q02763 # This protein is a protein tyrosine-kinase transmembrane receptor for angiopoietin 1. It may constitute the earliest mammalian endothelial cell lineage marker. Probably regulates endothelial cell proliferation, differentiation and guides the proper patterning of endothelial cells during blood vessel formation. ),NM_000459.2 |
| NCBI accession no. | NM_000459.2 |
| UniProt accession no. | Q02763 |
| relevant disease(s) | arthritis; obesity; osteoporosis; metabolic disorders |
| Gene Information | human ... TEK(7010) |
