General description
FABP1, also known as Fatty acid-binding protein, Liver Fatty acid-binding protein, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, or p14, and encoded by the gene FABP1/FABPL, is an important fatty acid binding and transport protein. FABP1 is produced in the liver and is part of a family of lipid carrier proteins. FABP1 facilitate the transfer of fatty acids between extra and intracellular membranes. FABP1 level in the blood is used as a biomarker for obesity and type II diabetes. Additionally, recent research indicates that FABP1 can modulate stellate cell activation and this may lead to diet-induced nonalcoholic fatty liver disease, thus FABP1 is a key focus of metabolic research.
~ 14 kDa observed
Immunogen
Recombinant protein corresponding to rat FABP1.
Application
Anti-FABP1 Antibody detects level of FABP1 & has been published & validated for use in FABP1.
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected FABP1 in wild type mouse liver cytosol and not in LFABP-1 -/- mouse liver cytosol.
Analysis Note
Evaluated by Western Blotting in human liver tissue lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected FABP1 in 10 µg of human liver tissue lysate.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | serum |
| antibody product type | primary antibodies |
| clone | polyclonal |
| species reactivity | human, mouse |
| species reactivity (predicted by homology) | rat (based on 100% sequence homology) |
| technique(s) | western blot: suitable |
| NCBI accession no. | NP_036688 |
| UniProt accession no. | P02692 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | rat ... Fabp1(24360) |
