产品介绍
Product Description
General description
PROX1（Prospero同源盒蛋白1）是果蝇Prospero的同源物，是一种含有同源盒的转录因子，可结合并充当肝受体同源物1（LRH1/NR5A2）的共受体。它是淋巴内皮细胞以及成肝细胞和肝细胞的特异性标志物。人Prox1与小鼠和大鼠Prox1具有97%的氨基酸序列一致性。
观察值〜95 kDa。Uniprot描述了83kDa的分子量，然而，由于SUMO化和/或替代起始位点，可在80-110kDa之间观察到该蛋白（Pan，M.R.，et al.（2009）.J Cell Sci. 122(Pt18):3358-3361.; Azuma, K., et al. (2011).Genes Cells.16(11):1063-1070.)。
Immunogen
KLH偶联的线性肽，对应于人Prospero同源盒蛋白1/PROX1的C末端。
Application
免疫组化分析：代表性批次的1：2,000的稀释液在小鼠E16胚胎丘脑组织中检测到Prospero同源盒蛋白1/PROX1（Prof. Samual Pleasure, University of California, San Francisco.）。
Alexa Fluor™是Life Technologies，Inc.的注册商标。
该抗Prospero同源盒蛋白1/PROX1抗体经验证可用于蛋白质印迹&IHC检测Prospero同源盒蛋白1/PROX1。
Analysis Note
通过蛋白质印迹在HEK293核提取物中进行了评估。
蛋白质印迹分析：该抗体的1：500稀释液在10 µg HEK293核提取物中检测到Prospero同源盒蛋白1/Prox1。
Other Notes
替代品：AB5475
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
技术参数
Specifications
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | mouse, rat |
| species reactivity (predicted by homology) | bovine (based on 100% sequence homology), fish (based on 100% sequence homology), chicken (based on 100% sequence homology), human (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| NCBI accession no. | NP_001257545 |
| UniProt accession no. | Q92786 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | mouse ... Prox1(19130) |
