产品介绍
Product Description
Application
Cirazoline hydrochloride has been used to activate the α1-noradrenergic receptors and to study the inhibitory effect of neurokinin1 (NK1) antagonists on respiratory activity using the brainstem transverse slice.
Biochem/physiol Actions
Cirazoline is a selective α1-adrenoceptor agonist and also a non-selective ligand for the imidazoline binding site. Cirazoline dereases spatial working memory performance in aged monkeys.
Features and Benefits
This compound is featured on the α1-Adrenoceptors and Imidazoline Binding Sites pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
技术参数
Specifications
| form | solid |
| Quality Level | 100 |
| color | white |
| solubility | H2O: >35 mg/mL |
| SMILES string | Cl[H].C1CN=C(COc2ccccc2C3CC3)N1 |
| InChI | 1S/C13H16N2O.ClH/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13;/h1-4,10H,5-9H2,(H,14,15);1H |
| InChI key | XFRXWLWUUDJHPB-UHFFFAOYSA-N |
| Gene Information | human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) |
