产品介绍
Product Description
Application
2′,5′-Dideoxyadenosine has been used to elucidate the mechanism of diligustilide (DLG). It has also been used to inhibit adenylate cyclase (AC).
Biochem/physiol Actions
Cell-permeable adenylyl cyclase inhibitor. IC50 = 2.7 μM in detergent-dispersed rat brain preparations.
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
Store at −20 °C after reconstitution.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥95% (HPLC) |
| form | solid |
| color | white |
| solubility | DMSO: soluble |
| storage temp. | −20°C |
| SMILES string | C[C@H]1O[C@H](C[C@@H]1O)n2cnc3c(N)ncnc23 |
| InChI | 1S/C10H13N5O2/c1-5-6(16)2-7(17-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7,16H,2H2,1H3,(H2,11,12,13)/t5-,6+,7-/m1/s1 |
| InChI key | FFHPXOJTVQDVMO-DSYKOEDSSA-N |
| Gene Information | rat ... Adcy2(81636) |
