产品介绍
Product Description
Biochem/physiol Actions
GANT58 is a Hedgehog signaling pathway inhibitor.
GANT58 is a Hedgehog signaling pathway inhibitor. GANT58 inhibits the hedgehog signaling pathway downstream of Smo. GANT58 inhibits Gli transcriptional activity, and reduces cellular levels of the Hh pathway components Gli1, Shh, and patched.
技术参数
Specifications
| assay | ≥98% (HPLC) |
| color | white to pale yellow |
| solubility | DMSO: >10 mg/mL |
| storage temp. | 2-8°C |
| SMILES string | c1cc(ccn1)-c2sc(-c3ccncc3)c(-c4ccncc4)c2-c5ccncc5 |
| InChI | 1S/C24H16N4S/c1-9-25-10-2-17(1)21-22(18-3-11-26-12-4-18)24(20-7-15-28-16-8-20)29-23(21)19-5-13-27-14-6-19/h1-16H |
| InChI key | USWLOKMMUTWFMD-UHFFFAOYSA-N |
