产品介绍
Product Description
Application
Nisoxetine has been used as a norepinephrine transport (NET) blocker in autoradiography studies. It has also been used as a NET blocker to study its effects on perivascular adipose tissue.
Biochem/physiol Actions
Nisoxetine is a selective and potent noradrenaline reuptake inhibitor. It has a high affinity towards the noradrenaline transporter. Nisoxetine possesses antidepressant activity.
Features and Benefits
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| storage condition | desiccated |
| color | white to beige |
| solubility | H2O: 20 mg/mL,ethanol: 50 mg/mL |
| SMILES string | Cl[H].CNCCC(Oc1ccccc1OC)c2ccccc2 |
| InChI | 1S/C17H21NO2.ClH/c1-18-13-12-15(14-8-4-3-5-9-14)20-17-11-7-6-10-16(17)19-2;/h3-11,15,18H,12-13H2,1-2H3;1H |
| InChI key | LCEURBZEQJZUPV-UHFFFAOYSA-N |
