产品介绍
Product Description
Biochem/physiol Actions
BIIL260 is a selective and potent leukotriene B4 (BLT1) receptor antagonist with a Ki value of 1.8 nM in human U937 cells. BIIL260 was used found to act as an inverse agonist, stabilizing the inactive state of BLT1.
Leukotriene B4 (BLT1) receptor antagonist
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | N\C(=N/[H])\c1ccc(cc1)OCc2cc(ccc2)COc3ccc(cc3)C(C)(C)c4ccc(cc4)O |
| InChI | 1S/C30H30N2O3/c1-30(2,24-8-12-26(33)13-9-24)25-10-16-28(17-11-25)35-20-22-5-3-4-21(18-22)19-34-27-14-6-23(7-15-27)29(31)32/h3-18,33H,19-20H2,1-2H3,(H3,31,32) |
| InChI key | MBLJFKQACMILLC-UHFFFAOYSA-N |
