产品介绍
Product Description
Biochem/physiol Actions
Nepafenac, a prodrug of amfenac, is used in the treatment of diabetic retinopathy. It is metabolized to its active form through intraocular enzymatic hydrolysis. Nepafenac has a molecular weight of 254.28 kDa and effectively penetrates through the cornea. Its molecule structure enables nepafenac to possess better permeability. Nepafenac has a low inhibitory effect on cyclooxygenase.
Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) that is routinely used in opthamology to control pain following cataract surgery.
Nepafenac is a NSAID (nonsteroidal anti inflammatory drug) used in opthamology.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | faintly yellow to dark yellow |
| solubility | DMSO: ≥5 mg/mL |
| storage temp. | room temp |
| SMILES string | NC(=O)Cc1cccc(c1N)C(=O)c2ccccc2 |
| InChI | 1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18) |
| InChI key | QEFAQIPZVLVERP-UHFFFAOYSA-N |
| Gene Information | human ... PTGS1(5742), PTGS2(5743) |
