产品介绍
Product Description
Biochem/physiol Actions
A-804598 is a P2X7 selective, competitive antagonist.
A-804598 is a P2X7 selective, competitive antagonist. In competition assays, the IC50s for human, rat and mouse channels are 11, 10 and 9 nM, respectively.
Features and Benefits
This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 10 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | N(c2c3c(nccc3)ccc2)\C(=N/[C@@H](C)c1ccccc1)\NC#N |
| InChI | 1S/C19H17N5/c1-14(15-7-3-2-4-8-15)23-19(22-13-20)24-18-11-5-10-17-16(18)9-6-12-21-17/h2-12,14H,1H3,(H2,22,23,24)/t14-/m0/s1 |
| InChI key | PQYCRDPLPKGSME-AWEZNQCLSA-N |
