Application
Aceclidine hydrochloride may be used in muscarinic acetylcholine receptor-mediated cell signaling studies.
Biochem/physiol Actions
Aceclidine at a concentration of 5 and 50 μg is capable of enhancing the outflow facility, following ciliary muscle disinsertion.
Aceclidine hydrochloride is a parasympathomimetic drug with weak anticholinesterase activity. It acts on cholinergic nerve-endings, lowers intraocular pressure and potent therapeutic agent for open-angle glaucoma.
Aceclidine is a non-selective muscarinic acetylcholine receptor partial agonist that is effective in reducing intraocular pressure.
Muscarinic receptor partial agonist
Features and Benefits
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to tan |
| solubility | H2O: ≥15 mg/mL at ~60 °C |
| storage temp. | −20°C |
| SMILES string | Cl.CC(=O)O[C@H]1CN2CC[C@H]1CC2 |
| InChI | 1S/C9H15NO2.ClH/c1-7(11)12-9-6-10-4-2-8(9)3-5-10;/h8-9H,2-6H2,1H3;1H/t9-;/m0./s1 |
| InChI key | LWWSARSTZGNKGV-FVGYRXGTSA-N |
