产品介绍
Product Description
Biochem/physiol Actions
GSK334429 is a selective histamine H3 receptor antagonist.
GSK334429 is a selective histamine H3 receptor antagonist. H3 antagonists increase the release of brain histamine, ACh, NE and DA neurotransmitters that modulate cognitive processes. Studies look at their analgesic efffects including efficacy for neuropathic pain.
Features and Benefits
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Other Notes
Store desiccated; dry room.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | H2O: 5 mg/mL (clear solution) |
| storage temp. | 2-8°C |
| SMILES string | Cl.CC(C)N1CCCN(CC1)C(=O)C2CCN(CC2)c3ccc(nc3)C(F)(F)F |
| InChI | 1S/C20H29F3N4O.ClH/c1-15(2)25-8-3-9-27(13-12-25)19(28)16-6-10-26(11-7-16)17-4-5-18(24-14-17)20(21,22)23;/h4-5,14-16H,3,6-13H2,1-2H3;1H |
| InChI key | RCZVWLOXPFGZDD-UHFFFAOYSA-N |
