产品介绍
Product Description
Biochem/physiol Actions
5-Ethyl-2′-deoxyuridine is an analog of pyrimidine, uridine. It is an effective antiviral agent and inhibits cell division in leukemic tumor cells. 5-Ethyl-2′-deoxyuridine interacts with 2′-deoxycytidine phosphate (dCTP) biosynthesis pathway to elicit antiproliferative effects.
5-Ethyl-2′-deoxyuridine (EUdR) is used as a 5-fluorouracil (FU) modulator. EtdUrd may be used to enhance the therapeutic index of 5-FU by reducing the catabolism, prolonging the plasma and intratumoral concentrations of 5-FU, and offering protection to normal organs by increasing the endogenous uridine levels.
Other Notes
Homolog of thymidine
技术参数
Specifications
| biological source | synthetic (organic) |
| Quality Segment | 200 |
| assay | ≥95% (HPLC) |
| form | powder |
| solubility | water: 50 mg/mL, clear, colorless to yellow |
| storage temp. | −20°C |
| SMILES string | CCC1=CN(C2CC(O)C(CO)O2)C(=O)NC1=O |
| InChI | 1S/C11H16N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15H,2-3,5H2,1H3,(H,12,16,17) |
| InChI key | XACKNLSZYYIACO-UHFFFAOYSA-N |
