产品介绍
Product Description
Biochem/physiol Actions
Sutezolid (PNU 100480) is an oxazolidinone antimicrobial. Sutezolid inhibits protein synthesis by inhibiting bacterial mRNA translation. Sutezolid is being investigated for the treatment of multiple drug–resistant and extensively drug-resistant tuberculosis. The compound is a less toxic and more potent derivative of linezolid.
Sutezolid (PNU 100480) is an oxazolidinone antimicrobial; antitubercular; inhibits bacterial mRNA translation.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| optical activity | [α]/D -8 to -12°, c = 1 in chloroform-d |
| color | white to beige |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | room temp |
| SMILES string | FC1=CC(N(C[C@H](CNC(C)=O)O2)C2=O)=CC=C1N3CCSCC3 |
| InChI | 1S/C16H20FN3O3S/c1-11(21)18-9-13-10-20(16(22)23-13)12-2-3-15(14(17)8-12)19-4-6-24-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1 |
| InChI key | FNDDDNOJWPQCBZ-ZDUSSCGKSA-N |
