产品介绍
Product Description
Biochem/physiol Actions
ATR-002, a derivate of CI-1040, is a cell penetrant, potent and specific inhibitor of the Raf/MEK/ERK pathway. ATR-002 exhibits strong anti-influenza and anti-SARS-CoV-2 activity. It impairs the influenzas and SARS-CoV-2 viruses induced expression of pro-inflammatory cytokines.
cell penetrant, potent and specific inhibitor of the Raf/MEK/ERK pathway; exhibits strong anti-influenza and anti-SARS-CoV-2 activity
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | O=C(C1=CC=C(C(F)=C1NC2=CC=C(C=C2Cl)I)F)O |
| InChI | 1S/C13H7ClF2INO2/c14-8-5-6(17)1-4-10(8)18-12-7(13(19)20)2-3-9(15)11(12)16/h1-5,18H,(H,19,20) |
| InChI key | XCNBGWKQXRQKSA-UHFFFAOYSA-N |
