产品介绍
Product Description
Biochem/physiol Actions
Cell penetrant, potent, and selective inhibitor of PARP7 that inhibits auto-MARylation and induced IFN-β in mouse colon carcinoma.
KMR-206 is a cell penetrant, potent, and selective inhibitor of PARP7 that inhibits auto-MARylation and induced IFN-β in mouse colon carcinoma (CT-26) cells. Also increased PARP7 protein levels in CT-26 cells.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥94% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | O=C(C1=CC(CC2=NNC(C3=C2C=C(C=C3)C#CC)=O)=CC=C1F)N4CCN(CC4)C5=NC=C(C=C5)C#N |
