产品介绍
Product Description
Biochem/physiol Actions
NAB2 is a cell permeable and selective modifier of α-synuclein toxicity diverse cell types and PD neurons. NAB2 restores Rsp5/Nedd4 E3 ligase-dependent endosomal and endoplasmic reticulum–to-Golgi vesicle trafficking.
NAB2 is a cell permeable and selective modifier of α-synuclein toxicity.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| storage temp. | 2-8°C |
| SMILES string | Clc1c(cccc1)CNC(=O)c2cc3nc[n](c3cc2)c4c(ccc(c4)C)C |
| InChI | 1S/C23H20ClN3O/c1-15-7-8-16(2)22(11-15)27-14-26-20-12-17(9-10-21(20)27)23(28)25-13-18-5-3-4-6-19(18)24/h3-12,14H,13H2,1-2H3,(H,25,28) |
| InChI key | CZSLEMCYYGEGKP-UHFFFAOYSA-N |
