General description
Indoleamine 2,3 dioxygenase (IDO) 1 is one of the four tryptophan catabolic enzymes in mammals. It codes for a full-length protein, made up of 403 amino acids and has a molecular weight of 45,332 Daltons. It is present in the cytosol. IDO1 is located on human chromosome 8p11.
Immunogen
Peptide with sequence CVLANWKKKDPNK, from the internal region of the protein sequence according to NP_002155.1
Biochem/physiol Actions
Indoleamine 2,3 dioxygenase (IDO) 1 plays an important role in the metabolism of tryptophan and in immune regulation. Removal of IDO1 results in attenuated contact hypersensitivity (CHS) responses.
Features and Benefits
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Physical form
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | goat |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable,indirect ELISA: suitable |
| UniProt accession no. | P14902 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... IDO1(3620) |
