产品介绍
Product Description
Biochem/physiol Actions
New MCE product August 2018. Engeletin is a flavanonol glycoside present in the skin of white grapes and white wine that exhibits anti-inflammatory activities. It inhibits LPS induced cytokines production in mouse J774A.1 macrophages. Also, engeletin attenuates LPS-induced endometritis in mice through inhibiting NF-κB activation, and inhibits inflammatory response in LPS-induced acute lung injury (ALI).
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| optical activity | [α]/D -13 to -17°, c = 0.5 in pyridine |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| web metadata keyword.default | (+)-(2R,3R)-Dihydrokaempferol 3-O-α-L-rhamnoside,(2R,3R)-Engelitin chemical,500mg Engeletin for laboratory analysis,ACS grade Engeletin powder,Dihydrokaempferol research grade,Engeletin LPS cytokine inhibitor,Engeletin NF-kB activation inhibitor,Engeletin anti-inflammatory compound for lab use,Engeletin flavanonol glycoside for research,Engeletin for acute lung injury research,Engeletin for endometritis studies,Engeletin for pharmaceutical applications,Sigma-Aldrich Engeletin 572-31-6,flavonoid Engeletin for biological studies |
| storage temp. | −20°C |
| SMILES string | O1[C@H]([C@@H]([C@@H]([C@H]([C@@H]1C)O)O)O)O[C@@H]2[C@H](Oc4c(c(cc(c4)O)O)C2=O)c3ccc(cc3)O |
| InChI | 1S/C21H22O10/c1-8-15(25)17(27)18(28)21(29-8)31-20-16(26)14-12(24)6-11(23)7-13(14)30-19(20)9-2-4-10(22)5-3-9/h2-8,15,17-25,27-28H,1H3/t8-,15-,17+,18+,19+,20-,21-/m0/s1 |
| InChI key | VQUPQWGKORWZII-WDPYGAQVSA-N |
