General description
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen
Peptide sequence around aa. 847-851 ( Q-Q-S-I-N ), according to the protein GRIA1.
Features and Benefits
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Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | ~110 kDa |
| species reactivity | human, rat, mouse |
| concentration | 1 mg/mL |
| technique(s) | western blot: 1:500-1:1000 |
| isotype | IgG |
| immunogen sequence | ( Q-Q-S-I-N) |
| NCBI accession no. | NP_000818.2 |
| UniProt accession no. | P42261 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... GRIA1(2890) |
