产品介绍
Product Description
Biochem/physiol Actions
BD064 is a probe-dependent and biased negative allosteric modulator (NAM) of the chemokine receptor CXCR3 signaling that preferentially inhibits CXCL11-mediated ?-arrestin 2 recruitment over G protein activation.
biased negative allosteric modulator of the chemokine receptor CXCR3 signaling that preferentially inhibits CXCL11-mediated β-arrestin 2 recruitment
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | −20°C |
| SMILES string | O=C1N(C2=CC=C(OCC)C=C2)C(C(N(C(CC3=CC=C(F)C(C(F)(F)F)=C3)=O)CC4=CC(B(O)O)=C(F)C=C4)C)=NC5=NC=CC=C51 |
