产品介绍
Product Description
Biochem/physiol Actions
RIPK2 inhibitor 1 is a potent and selective inhibitor of Receptor interacting protein kinase 2 (RIPK2) that potently inhibit NFκB activity and the proliferation of cancer cell lines. RIPK2 inhibitor 1 inhibits intestinal and lung inflammation in rodent models.
potent and selective inhibitor of Receptor interacting protein kinase 2 (RIPK2) that potently inhibit NFκB activity
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to very dark gray |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | CC1=CC=C(C(NC2=CC(C3=NC=CN3C)=CC=C2)=O)C=C1NC(C4=CC=CC=C4)=O |
| InChI | 1S/C25H22N4O2/c1-17-11-12-20(16-22(17)28-24(30)18-7-4-3-5-8-18)25(31)27-21-10-6-9-19(15-21)23-26-13-14-29(23)2/h3-16H,1-2H3,(H,27,31)(H,28,30) |
| InChI key | OIIYBZHRYXJCHR-UHFFFAOYSA-N |
