General description
The antibody MEM-48 recognizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit; beta2 integrin). CD18 is a 90-95 kDa type I transmembrane protein expressed on all leukocytes.
Immunogen
Leukocytes of a patient suffering from a LGL-type leukemia
Application
The reagent is designed for Flow Cytometry analysis. Suggested working dilution for Flow Cytometry is 2 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.
Features and Benefits
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Physical form
Solution in azide free phosphate buffered saline, pH 7.4; 0.2 um filter sterilized. Endotoxin level is less than 0.01 EU/ug of the protein, as determined by the LAL test.
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | MEM-48, monoclonal |
| form | buffered aqueous solution |
| species reactivity | human |
| concentration | 1 mg/mL |
| technique(s) | flow cytometry: suitable |
| impurities | ≤1 EU/μg endotoxin (LAL test) |
| isotype | IgG1 |
| NCBI accession no. | NM_000211.3 |
| UniProt accession no. | P05107 |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| target post-translational modification | unmodified |
| Gene Information | human ... ITGB2(3689) |
