产品介绍
Product Description
Biochem/physiol Actions
8-Azaguanine is a triazole-antimetabolite that displays varies pharmacological effects including anticancer, antiviral and antifungal. It is easily incorporated into ribonucleic acids including rRNA and tRNA. 8-Azaguanine appears to alter mRNA splicing in SF3B1 mutant cells. 8-Azaguanine novel immunomodulatory drug (IMiD) that significantly increases the cytotoxicity of NK cells.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| mp | >300 °C (lit.) |
| solubility | DMSO: 2 mg/mL, clear (warmed) |
| storage temp. | 2-8°C |
| SMILES string | NC1=Nc2[nH]nnc2C(=O)N1 |
| InChI | 1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11) |
| InChI key | LPXQRXLUHJKZIE-UHFFFAOYSA-N |
