产品介绍
Product Description
Biochem/physiol Actions
Selective and efficacious in vivo inhibitor of ferroptosis-suppressor-protein 1 (FSP1); ferroptosis inducer.
icFSP1 is a selective and efficacious in vivo inhibitor of ferroptosis-suppressor-protein 1 (FSP1). icFSP1 triggers subcellular relocalization of FSP1 from the membrane and initiate FSP1 reversible aggregation into liquid droplet-like structures before ferroptosis initiation. It synergizes with ferroptosis inducing agents to potentiate the ferroptotic cell death response.
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥95% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | CC1=NC2=C(C(N1C3=CC=C(NC(CC4=CC(OC)=C(OC)C(OC)=C4)=O)C=C3)=O)C=CC=C2 |
