产品介绍
Product Description
Biochem/physiol Actions
TP053 is a potent thienopyrimidine antitubercular agent that kills both replicating and nonreplicating Mycobacterium tuberculosis. It appears that TP053 is a prodrug, which is activated by mycothiol-dependent reductase Rv2466c.
potent thienopyrimidine antitubercular agent that kills both replicating and nonreplicating Mycobacterium tuberculosis.
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| color | yellow to orange |
| solubility | DMSO: 2 mg/mL, clear (warmed) |
| storage temp. | 2-8°C |
| SMILES string | CNC1=NC(C2=CC=CC=C2)=NC3=C1C=C(S3)[N+]([O-])=O |
| InChI | 1S/C13H10N4O2S/c1-14-12-9-7-10(17(18)19)20-13(9)16-11(15-12)8-5-3-2-4-6-8/h2-7H,1H3,(H,14,15,16) |
| InChI key | JHLJMVJTSFLRPS-UHFFFAOYSA-N |
