产品介绍
Product Description
Biochem/physiol Actions
IDT307 (APP+) is a fluorescent analogue of the dopaminergic neurotoxin MPP+ monoamine transporter substrate that fluoresces after uptake into cells. IDT307 is a substrate for the dopamine transporter (DAT), norepinephrine transporter (NET), and serotonin transporter (SERT). IDT307 (APP+) was found to label catecholamine neuronal cell bodies with high selectivity in midbrain and was used to investigate SERT function in lymphocytes and platelets.
IDT307 (APP+) is a fluorescent analogue of the dopaminergic neurotoxin MPP+.
Features and Benefits
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | , orange to dark orange-red |
| solubility | DMSO: 15 mg/mL, clear |
| storage temp. | −20°C |
| SMILES string | [I-].[n+]1(ccc(cc1)c2ccc(cc2)N(C)C)C |
| InChI | 1S/C14H17N2.HI/c1-15(2)14-6-4-12(5-7-14)13-8-10-16(3)11-9-13;/h4-11H,1-3H3;1H/q+1;/p-1 |
| InChI key | CAMWVBRDIKKGII-UHFFFAOYSA-M |
