产品介绍
Product Description
General description
H-7 dihydrochloride blocks human immunodeficiency virus (HIV-1) replication in MOLT-4 (clone No. 8) cell line. It increases the secretion of interleukin 1β (IL-1β).
Application
H-7 dihydrochloride has been used to study H-7-induced inhibition of contractility in rat embryo fibroblasts (REF52) cells and acts as a kinase inhibitor.
Biochem/physiol Actions
Inhibitor of cyclic nucleotide dependent protein kinase (PKA) and protein kinase C.
Disclaimer
Light sensitive
技术参数
Specifications
| Quality Level | 200 |
| assay | ≥98% (HPLC) |
| form | powder |
| solubility | H2O: 20 mg/mL |
| storage temp. | 2-8°C |
| SMILES string | Cl.Cl.CC1CNCCN1S(=O)(=O)c2cccc3cnccc23 |
| InChI | 1S/C14H17N3O2S.2ClH/c1-11-9-16-7-8-17(11)20(18,19)14-4-2-3-12-10-15-6-5-13(12)14;;/h2-6,10-11,16H,7-9H2,1H3;2*1H |
| InChI key | OARGPFMFRLLKPF-UHFFFAOYSA-N |
| Gene Information | human ... PRKCA(5578), PRKCB(5579), PRKCD(5580), PRKCE(5581), PRKCG(5582), PRKCH(5583), PRKCI(5584) |
