Application
Nefopam hydrochloride has been used as a standard for the quantitative determination of tramadol by gas chromatography–mass spectrometry (GC/MS).
Biochem/physiol Actions
Nefopam is a centrally-acting analgesic drug of the benzoxazocine chemical class. Nefopam is a non-opioid, but has a potentiating effect on morphine and other opioids. Its mechanism of action is not certain, but may involve its action as a dopamine/serotonin/norepinephrine reuptake inhibitor.
Nefopam is a centrally-acting non-opioid analgesic drug of the benzoxazocine chemical class.
Features and Benefits
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| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | white to beige |
| mp | 260 °C (dec.) (lit.) |
| solubility | H2O: 5 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | Cl.CN1CCOC(c2ccccc2)c3ccccc3C1 |
| InChI | 1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18;/h2-10,17H,11-13H2,1H3;1H |
| InChI key | CNNVSINJDJNHQK-UHFFFAOYSA-N |
