产品介绍
Product Description
Application
Rc-Ome may be used in GABAA-mediated cell signaling studies.
Biochem/physiol Actions
Rc-OMe is a GABAA PAM
Rc-OMe is a GABAA PAM that distinguishes α1β2γ2s from α1β2 receptors. The compound has very weak potentiating effects on α1β2, but potentiates GABA-elicited currents of α(123)β2γ2s receptors, all with low μM EC50s. Rc-OMe acts at a binding site that is distinct from BDZ, pentobarbital and loreclezole modulatory sites.
Features and Benefits
This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | , light to dark yellow |
| solubility | DMSO: ≥10 mg/mL |
| storage temp. | 2-8°C |
