General description
Interferon-γ (IFN-γ) belongs to Type II class of interferons and is produced by T helper cells (specifically, Th1 cells), natural killer (NK) and natural killer T (NKT) cells and cytotoxic T cells (TC cells) . It has various biological functions including antiviral activity like inhibition of cell or tumor growth, act as a potent modulator of immune responses and modifies cellular processes as well as stimulates the differentiation of B cells into immunoglobulin-producing cells. Monoclonal Anti-Interferon-γ antibody can be used in immunoblotting. Rat anti-Interferon-γ antibody has shown no cross-reactivity for recombinant human IFN-γ or recombinant rat IFN-γ.
Immunogen
recombinant mouse IFN-γ.
Application
Monoclonal Anti-Interferon-γ antibody can be used in neutralization and indirect ELISA.
Biochem/physiol Actions
The antibody does not cross-react with recombinat human IFN-γ or recombinant rat IFN-γ.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline and 5% trehalose.
Preparation Note
Purified from cell culture supernatant using protein G.
| biological source | rat |
| Quality Level | 200 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 37895, monoclonal |
| form | lyophilized powder |
| species reactivity | mouse |
| technique(s) | flow cytometry: suitable,neutralization: suitable,western blot: suitable |
| isotype | IgG2a |
| UniProt accession no. | P01580 |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | mouse ... Ifng(15978) |
